Physician-Supervised Weight Loss Injections: Dr. Mills’ Story

Posted in Weight Loss

There’s not a diet that I did not try. I failed with most or all of them, as those that know me can attest. There’s no question that I’m insulin resistant and that that has been a problem for me my whole life. You put that together with how the food industry makes food more addictive by increasing all the carbs and adding sugar to it, and it’s no wonder that we as a nation have gotten to be the fattest in the world. 

My whole life, I would “live to eat” instead of “eat to live.” I never met a carb that didn’t love me and I loved incredibly. Once physician-guided weight loss injections came out, then and only then was I able to lose 90 pounds so far. If I was going to be able to live any longer, I had to do that.

Some of us that are insulin resistant just could not get ahead. Everybody would say, “You can do it” with diet exercise, but these injections also have hormones in them that make you not wake up at 2 AM and crave a pizza! These have been life-changing for me and I think they can be for you too – and for a large portion of the United States.

This past year was the very first time in 40 years that the actual weight of people in the United States went down. There were 20 million people that were on these drugs to help them lose weight. The biggest killer in the United States is heart disease, and that has been shown to be very closely coupled with insulin resistance and gaining weight as has even cancer rates and dementia. 

I’m happy to try to help you on a journey that has been liberating for me, but let’s do it in a controlled, smart fashion by looking at some of your bio markers ahead of time and see if doing this changes things for you. 

There are so many great benefits for individuals outside of an obese BMI range. It helps prevent the pre-existing conditions they list as qualifiers. Prevention is key to health. As age increases, insulin resistance increases, and it has been so helpful in women who are post menopausal. I agree the bar should be lowered and each patient considered on an individual basis.

GLP-1 therapy has shown significant promise for individuals struggling with metabolic dysfunction, even when their BMI alone may not fully reflect the clinical need. Many people experience persistent insulin resistance, elevated fasting glucose, difficulty managing appetite, and increased visceral fat despite efforts with diet and exercise. These are clear indicators of underlying metabolic imbalance, which GLP-1s directly target by improving insulin sensitivity, supporting glucose regulation, and enhancing satiety.

Patients in transitional life stages, such as menopause, are particularly vulnerable to these shifts due to changes in hormone levels that affect metabolism, fat distribution, and glucose control. These subtle yet impactful changes often go unaddressed under current BMI-based prescribing guidelines. By expanding access to GLP-1 therapy beyond rigid weight criteria, providers can offer a more individualized and preventative approach, one that supports long-term cardiometabolic health and reduces the risk of progression to chronic disease.

– Daniel C. Mills, MD, FACS

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